Neoplasia Diagnosis After Multi-target Stool DNA Is Enhanced Among Lowest Baseline Detectors.
Derek W EbnerKelli N BurgerDouglas W MahoneyBrendan T BroderickJason D EckmannMary E DevensKari L LowrieJohn B LeagueJamie BeringAllon KahnEduardo A RodriguezDavid O PrichardMichael B WallaceSunanda V KaneJonathan A LeightonNavtej S ButtarLila J Finney RuttenSuryakanth R GuruduJohn B KisielPublished in: Digestive diseases and sciences (2023)
Knowledge of + mt-sDNA enriches neoplasia diagnosis compared to average risk screening exams. Adenomatous and serrated lesion diagnosis was magnified among those with lower adenoma detection rates. Awareness of the mt-sDNA result may increase physician attention during colonoscopy. Pre-procedure knowledge of a positive mt-sDNA test improves neoplasia diagnosis rates among colonoscopists with lower baseline adenoma detection rates, independent of withdrawal time.