HBV X protein-based therapeutic vaccine accelerates viral antigen clearance by mobilizing monocyte infiltration into the liver in HBV carrier mice.

Jau-Hau HorngWei-Hsiang LinChang-Ru WuYou-Yu LinLi-Ling WuDing-Shinn ChenPei-Jer Chen

Published in: Journal of biomedical science (2020)

We report the potential role of HBx as a major immunogen in an HBV therapeutic vaccine and the significance of a liver-infiltrating monocyte subset during hepatic viral clearance.

Keyphrases

hepatitis b virus
liver failure
dendritic cells
sars cov
endothelial cells
peripheral blood
type diabetes
binding protein
high fat diet induced
protein protein
human health
metabolic syndrome
skeletal muscle
amino acid
wild type
small molecule