Classification of Alzheimer's Disease Based on Weakly Supervised Learning and Attention Mechanism.
Xiaosheng WuShuangshuang GaoJunding SunYu-Dong ZhangShuihua WangPublished in: Brain sciences (2022)
The brain lesions images of Alzheimer's disease (AD) patients are slightly different from the Magnetic Resonance Imaging of normal people, and the classification effect of general image recognition technology is not ideal. Alzheimer's datasets are small, making it difficult to train large-scale neural networks. In this paper, we propose a network model (WS-AMN) that fuses weak supervision and an attention mechanism. The weakly supervised data augmentation network is used as the basic model, the attention map generated by weakly supervised learning is used to guide the data augmentation, and an attention module with channel domain and spatial domain is embedded in the residual network to focus on the distinctive channels and spaces of images respectively. The location information enhances the corresponding features of related features and suppresses the influence of irrelevant features.The results show that the F1-score is 99.63%, the accuracy is 99.61%. Our model provides a high-performance solution for accurate classification of AD.
Keyphrases
- deep learning
- machine learning
- working memory
- magnetic resonance imaging
- big data
- neural network
- artificial intelligence
- convolutional neural network
- cognitive decline
- end stage renal disease
- electronic health record
- optical coherence tomography
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prognostic factors
- resting state
- multiple sclerosis
- high resolution
- healthcare
- social media
- rna seq
- high density
- functional connectivity
- single cell