Assessment of Brain Glucose Metabolism Following Cardiac Arrest by [18F]FDG Positron Emission Tomography.

Hannah J ZhangSamuel MitchellYong-Hu FangHsiu-Ming TsaiLin PiaoAlaa OustaLara LeoniChin-Tu ChenWillard W Sharp

Published in: Neurocritical care (2021)

This study has successfully applied [18F]FDG-PET/CT to measure changes in brain metabolism in a murine model of asystolic CA. Our results demonstrate increased [18F]FDG uptake in the brain 72 h following CA, suggesting increased metabolic demand in the case of severe neurological injury. Further study is warranted to determine the etiology of these changes.

Keyphrases

positron emission tomography
computed tomography
cardiac arrest
pet ct
pet imaging
resting state
white matter
functional connectivity
multiple sclerosis
early onset
brain injury