Bone-Targeted Dual Functional Lipid-coated Drug Delivery System for Osteosarcoma Therapy.

Jie ZhongWeiye WenJinjin WangMengyu ZhangYijiang JiaXiaowei MaYu-Xiong SuYuji WangXinmiao Lan

Published in: Pharmaceutical research (2022)

By providing a highly biocompatible platform for osteosarcoma therapy, LCA NPs may help to significantly enhance the anticancer effect of Pt and greatly reduce the systemic toxicity and side effects of Pt towards osteosarcoma.

Keyphrases

oxidative stress
stem cells
cancer therapy
drug delivery
body composition
mesenchymal stem cells
cell therapy
single cell
drug induced