A stable nanoscaled Zr-MOF for the detection of toxic mycotoxin through a pH-modulated ratiometric luminescent switch.

Xiaolei GuoNansong ZhuYue LouSiyuan RenShirui PangYiqiang HeXiao-Bo Chen Zhan Shi Shouhua Feng

Published in: Chemical communications (Cambridge, England) (2020)

A stable nanoscaled single-excitation ratiometric luminescent pH sensor (MPDB-PCN) over a broad pH range from 2.5 to 8.6 is fabricated through post-synthetic modification of PCN-224 with naphthalimide-derived molecules. Due to the rapid, sensitive and linear response to pH, MPDB-PCN is capable of detecting 3-nitropropionic acid (3-NPA), an acid neurotoxin in food safety, with a low detection limit of 15 μM in sugarcane juice.

Keyphrases

sensitive detection
loop mediated isothermal amplification
quantum dots
energy transfer
fluorescent probe
living cells
metal organic framework
hydrogen peroxide
label free
real time pcr
pet imaging
climate change
human health