Discontinuation of biosimilar infliximab in Japanese patients with rheumatoid arthritis achieving sustained clinical remission or low disease activity during the IFX-SIRIUS STUDY I (the IFX-SIRIUS STUDY II): Study protocol for an interventional, multicenter, open-label, single-arm clinical trial with clinical, ultrasound and biomarker assessments.

Toshimasa ShimizuShin-Ya KawashiriShuntaro SatoShimpei MorimotoShuri MinodaYurika KawazoeShohei KurodaShigeki TashiroRemi SumiyoshiNaoki HosogayaHiroshi YamamotoAtsushi Kawakami

Published in: Medicine (2020)

This study was registered in the Japan Registry of Clinical Trials (https://jrct.niph.go.jp) on April 20, 2020 as jRCTs071200007.

Keyphrases

clinical trial
disease activity
open label
rheumatoid arthritis
systemic lupus erythematosus
computed tomography
study protocol
double blind
ultrasound guided
ulcerative colitis