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Changes in chemical and ultrastructural composition of ameroid constrictors following in vitro expansion.

Thomas S AndersonGraham A RanceLong JiangMatthew J PiggottElinor J FieldGuillaume P Chanoit
Published in: PloS one (2018)
There is a high degree of inter- and intra-constrictor homogeneity from different batches, and reproducible ultrastructural changes following in vitro expansion. Variations occur in both the surface chemistry and topography of the device during closure, which can potentially affect the biomaterial-host interface. Ameroid constrictor closure mechanism is likely involving calcium-mediated inter-protein interactions rather than the imbibition of water only.
Keyphrases
  • electron microscopy
  • resting state
  • amino acid
  • tissue engineering