Genomic Analysis of Group B Streptococcus from Neonatal Sepsis Reveals CC17 Clonal Expansion and Insights into Virulence- and Resistance-Associated Traits After Intrapartum Antibiotic Prophylaxis.

The study revealed the expansion of GBS CC17 and the increase of LOD that occurred simultaneously with the implementation of IAP. Although the susceptibility of CC17 to antimicrobial agents is not different from other sequence types at present, GBS with phenotypic resistance to antimicrobials may emerge in the future given the environmental selection pressure and the continued accumulation of SNP mutations.