Bacterial superinfection pneumonia in SARS-CoV-2 respiratory failure.

Chiagozie O Pickens Catherine Aiyuan Gao Michael J Cuttica Sean B Smith Lorenzo L Pesce Rogan A Grant Mengjia Kang Luisa Morales-Nebreda Avni A Bavishi Jason Arnold Anna E Pawlowski Chao Qi G R Scott Budinger Benjamin David Singer Richard G Wunderink

Published in: medRxiv : the preprint server for health sciences (2021)

With use of sensitive diagnostic tools, bacterial superinfection at the time of intubation is infrequent in patients with severe SARS-CoV-2 pneumonia. Treatment based on current guidelines would result in substantial antibiotic overuse. The incidence rate of VAP in ventilated patients with SARS-CoV-2 pneumonia are higher than historically reported.

Keyphrases

sars cov
respiratory failure
extracorporeal membrane oxygenation
respiratory syndrome coronavirus
mechanical ventilation
acute respiratory distress syndrome
intensive care unit
cardiac arrest
clinical practice
community acquired pneumonia