Circulating primary bile acid is correlated with structural remodeling in atrial fibrillation.
Xin-Hua WangZheng LiMin-Hua ZangTian-Bao YaoJia-Liang MaoJun PuPublished in: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing (2019)
The higher circulating level of CDCA in AF than in PSVT, positive correlation of CDCA with LVA in AF, and incubation dose-dependent increase of mouse atrial myocyte apoptosis indicated that CDCA might play a significant role in the progress of structural remodeling of AF.
Keyphrases
- atrial fibrillation
- catheter ablation
- left atrial
- oral anticoagulants
- left atrial appendage
- direct oral anticoagulants
- heart failure
- percutaneous coronary intervention
- oxidative stress
- endoplasmic reticulum stress
- cell death
- cell cycle arrest
- acute coronary syndrome
- coronary artery disease
- cell proliferation
- venous thromboembolism