Distinct peripheral vs mucosal T-cell phenotypes in chlamydia-infected women.
Brian M O OgendiRakesh K BakshiSteffanie SabbajLaDraka' BrownJeannette Y LeeRicha KapilWilliam M GeislerPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2017)
T-cell phenotypes differed in the peripheral vs genital mucosa compartments in chlamydia-infected women. As chlamydia infects mucosal epithelial cells, the finding of a higher frequency of activated T-cells and Th-1 phenotypes in the mucosa likely reflects an adaptive immune response to infection.