Evidence of Placental Villous Inflammation and Apoptosis in Third-Trimester Symptomatic SARS-CoV-2 Maternal Infection.

Manggala Pasca Wardhana Kuntaman Kuntaman Budi Utomo Rozi Aditya Aryananda Salsabila Nabilah Rifdah Ifan Ali Wafa Almira Aulia Shahnaz Dahlia Ningrum Nareswari Imanadha Cininta Grace Ariani Jan M M van Lith Erry Gumilar Dachlan

Published in: Yonsei medical journal (2024)

The presence of SARS-CoV-2 spike protein as well as altered inflammatory and apoptotic processes may indicate the presence of placental disturbance in third-trimester maternal COVID-19 infection. The lack of correlation between placental disruption and maternal severity status suggests the need for more research to understand the infection process and any potential long-term impacts on all offsprings born to COVID-19-infected pregnant women.

Keyphrases

sars cov
pregnancy outcomes
pregnant women
birth weight
gestational age
oxidative stress
respiratory syndrome coronavirus
cell death
preterm birth
endoplasmic reticulum stress
cell cycle arrest
cell proliferation
low birth weight
risk assessment
binding protein
climate change