Comparing the effect of bone marrow mono-nuclear cells with mesenchymal stem cells after acute myocardial infarction on improvement of left ventricular function: a meta-analysis of clinical trials.
Alireza HosseinpourFatemeh KheshtiAsma KazemiArmin AttarPublished in: Stem cell research & therapy (2022)
Our results showed that transplantation of MSCs after AMI might increase LVEF more than BM-MNCs; also, based on ICEMAN, there was likely effect modification between subgroups although uncertainty still remained.
Keyphrases
- mesenchymal stem cells
- acute myocardial infarction
- left ventricular
- bone marrow
- umbilical cord
- clinical trial
- percutaneous coronary intervention
- induced apoptosis
- cell therapy
- cell cycle arrest
- hypertrophic cardiomyopathy
- mitral valve
- left atrial
- aortic stenosis
- endoplasmic reticulum stress
- stem cells
- acute coronary syndrome
- cell proliferation
- study protocol