Screening for trisomies by cfDNA testing of maternal blood in twin pregnancy: update of The Fetal Medicine Foundation results and meta-analysis.

María Del Mar GilS GalevaJacques C JaniL KonstantinidouRanjit Akolekar Maria N PlanaK H Nicolaides

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2019)

The performance of cfDNA testing for trisomy 21 in twin pregnancy is similar to that reported in singleton pregnancy and is superior to that of the first-trimester combined test or second-trimester biochemical testing. The number of cases of trisomies 18 and 13 is too small for accurate assessment of the predictive performance of the cfDNA test. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd.

Keyphrases

preterm birth
pregnancy outcomes
gestational age
birth weight
pregnant women
systematic review
high resolution
physical activity
weight gain