Jagged Ends on Multinucleosomal Cell-Free DNA Serve as a Biomarker for Nuclease Activity and Systemic Lupus Erythematosus.

Spencer C DingRebecca W Y ChanWenlei PengLiangbo HuangZe ZhouXi HuStefano VolpiLinda T HirakiAugusto VaglioParide FenaroliPaola BoccaLai Shan TamPriscilla C H WongLydia H P TamPeiyong JiangRossa W K ChiuAllen K C ChanY M Dennis Lo

Published in: Clinical chemistry (2022)

Detailed understanding of the relationship between nuclease and plasma DNA jaggedness has opened up avenues for biomarker development.

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