Differential involvement of ipsilateral and contralateral spinal cord astrocyte D-serine in carrageenan-induced mirror-image pain: role of σ1 receptors and astrocyte gap junctions.

Hoon-Seong ChoiDae-Hyun RohSeo-Yeon YoonSheu-Ran ChoiSoon-Gu KwonSuk-Yun KangJi-Young MoonHo-Jae HanAlvin J BeitzJang Hern Lee

Published in: British journal of pharmacology (2018)

Spinal astrocyte D-serine plays an important role in the development of mirror-image pain. Furthermore, σ1 receptors and astrocyte gap junction signalling mediate ipsilateral and contralateral D-serine production respectively.

Keyphrases

spinal cord
neuropathic pain
chronic pain
pain management
protein kinase
deep learning
spinal cord injury
high glucose
single molecule
machine learning
drug induced