Decline in Carbon Monoxide Transfer Coefficient in Chronic Obstructive Pulmonary Disease.
Yeon Wook KimChang-Hoon LeeHun-Gyu HwangYu-Il KimDeog-Kyeom KimYeon-Mok OhSang Haak LeeKi Uk KimSang-Do LeePublished in: Journal of clinical medicine (2020)
Most patients with COPD experienced Kco decline over time, which was greater in patients with more severe airflow limitation and emphysema. Decline in Kco was associated with an accelerated decline in FEV1 and more frequent exacerbations; hence, this should be considered as an important outcome measure in further studies.