Is Olfactory Epithelium Biopsy Useful for Confirming Alzheimer's Disease?

Maria Dantas Costa Lima GodoyMarco Aurélio FornazieriRichard L DotyFábio de Rezende PinnaJosé Marcelo FarfelGlaucia Bento Dos SantosMariana MolinaRenata E L Ferretti-RebustiniRenata E P LeiteClaudia K SuemotoLea T GrinbergCarlos A G PasqualucciRichard Louis VoegelsRicardo NitriniWilson Jacob Filho

Published in: The Annals of otology, rhinology, and laryngology (2018)

AD-related biomarker heterogeneity, which has not been previously demonstrated, makes comparisons across studies difficult and throws into question the usefulness of OE amyloid-beta and PHF-tau biopsies in detecting AD.

Keyphrases

ultrasound guided
single cell
cognitive decline
fine needle aspiration
cerebrospinal fluid
case control
mild cognitive impairment