Depression with atypical neurovegetative symptoms shares genetic predisposition with immuno-metabolic traits and alcohol consumption.

Isabella BadiniJonathan R I ColemanSaskia P HagenaarsMatthew HotopfGerome BreenCathryn M LewisChiara Fabbri

Published in: Psychological medicine (2020)

↑WS depression shows evidence of distinct genetic predisposition to immune-metabolic traits and alcohol consumption. These genetic signals suggest that biological targets including immune-cardio-metabolic pathways may be relevant to therapies in individuals with ↑WS depression.

Keyphrases

alcohol consumption
genome wide
sleep quality
depressive symptoms
copy number
dna methylation