Extracellular matrix production and oxygen diffusion regulate chemotherapeutic response in osteosarcoma spheroids.

Isabel S SaghebThomas P CoonanR Lor RandallKatherine H Griffin J Kent Leach

Published in: Cancer medicine (2024)

This work establishes OS spheroids as a valuable tool for early OS tumor formation investigation and holds potential for novel therapeutic target and prognostic indicator discovery.

Keyphrases

extracellular matrix
small molecule
high throughput
human health
risk assessment
climate change