Metagenome-wide analysis uncovers gut microbial signatures and implicates taxon-specific functions in end-stage renal disease.

Pan ZhangXifan WangShenghui LiXuesen CaoJianzhou ZouYi FangYiqin ShiFangfang XiangBo ShenYixuan LiBing FangYue ZhangRuochun GuoQingbo LvLiwen ZhangYufei LuYaqiong WangJinbo YuYeqing XieRan WangXiaohong ChenJiawei YuZhen ZhangJingjing HeJing ZhanWenlv LvYuxin NieJieru CaiXialian XuJiachang HuQi ZhangTing GaoXiaotian JiangXiao TanNing XueYimei WangYimei RenLi WangHan ZhangYichun NingJing ChenLin ZhangShi JinFazheng RenStanislav Dusko EhrlichLiang ZhaoXiaoqiang Ding

Published in: Genome biology (2023)

This study delineates the taxonomic and functional landscapes and biomarkers of the ESRD microbiome. Understanding the role of gut microbiota in ESRD could open new avenues for therapeutic interventions and personalized treatment approaches in patients with this condition.

Keyphrases

end stage renal disease
chronic kidney disease
peritoneal dialysis
physical activity
minimally invasive
gene expression
dna methylation