Physiological correction of hereditary mild hypofibrinogenemia during pregnancy.
Rita MarchiStéphane DuralOcéane PecheuxMarguerite Neerman-ArbezAlessandro CasiniPublished in: Haemophilia : the official journal of the World Federation of Hemophilia (2023)
In this case of hereditary mild hypofibrinogenemia we observed a physiological increase of fibrinogen and thrombin generation. Future studies should focus on moderate and severe hypofibrinogenemia, to assess fibrinogen variation and the overall impact of increased TG on the hemostasis balance.