X-chromosome inactivation pattern of amniocytes predicts the risk of dystrophinopathy in fetal carriers of DMD mutations.

Wen-Bin HeJuan DuPing-Yuan XieShuang ZhouYa-Xin ZhangGuang-Xiu LuGe LinWen LiYue-Qiu Tan

Published in: Prenatal diagnosis (2019)

XCI was significantly implicated in symptomatic female carriers of dystrophinopathies, and XCI pattern analysis of amniocytes may be useful in predicting the risk of dystrophinopathy in fetal carriers.

Keyphrases

duchenne muscular dystrophy
copy number
gene expression