Hypertension, seizures, and epilepsy: a review on pathophysiology and management.
Sara GaspariniEdoardo FerlazzoChiara SueriVittoria CianciMichele AscoliSalvatore M CavalliEttore BeghiVincenzo BelcastroAmedeo BianchiPaolo BennaRoberto CantelloDomenico ConsoliFabrizio A De FalcoGiancarlo Di GennaroAntonio GambardellaGian Luigi GigliAlfonso IudiceAngelo LabateRoberto MichelucciMaurizio PaciaroniPasquale PalumboAlberto PrimaveraFerdinando SartucciPasquale StrianoFlavio VillaniEmilio RussoGiovambattista De SarroUmberto Aguglianull nullPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2019)
Current evidence from preclinical and clinical studies supports the vision that hypertension may be a cause of seizures and epilepsy through direct or indirect mechanisms. In both post-stroke epilepsy and small vessel disease-associated epilepsy, chronic antiepileptic treatment is recommended. In posterior reversible encephalopathy syndrome blood pressure must be rapidly lowered and prompt antiepileptic treatment should be initiated.