Refractory chronic urticaria in adults: clinical characterization and predictors of severity.

Iolanda Alen CoutinhoFrederico Soares RegateiroRosa Anita FernandesJoana Sofia PitaRaquel GomesConstança CoelhoAna Todo Bom

Published in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2020)

Autoimmunity can affect about half of the patients with severe or long-term CU. UAS7 and angioedema are associated with disease exacerbations. UAS7 and UCT presented unequal accuracy, with UAS7 better associating with the occurrence of exacerbations and treatment doses. Patients with refractory CU frequently present psychiatric disorders. Accurate diagnostic tests, namely autoimmune parameters and inflammatory markers, should be recommended in some individual cases.

Keyphrases

chronic obstructive pulmonary disease
cystic fibrosis
risk assessment
drug induced
multiple sclerosis
early onset
high resolution
metal organic framework
combination therapy