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Blood pressure-lowering treatment strategies based on cardiovascular risk versus blood pressure: A meta-analysis of individual participant data.

Kunal N KarmaliDonald M Lloyd-JonesJoep van der LeeuwDavid C GoffSalim YusufAlberto ZanchettiPaul P GlasziouRodney JacksonMark WoodwardAnthony RodgersBruce C NealEivind BergeKoon TeoBarry R DavisJohn ChalmersCarl PepineKazem RahimiJohan Sundströmnull null
Published in: PLoS medicine (2018)
A blood pressure-lowering treatment strategy based on predicted cardiovascular risk is more effective than one based on blood pressure levels alone across a range of thresholds. These results support using cardiovascular risk assessment to guide blood pressure treatment decision-making in moderate- to high-risk individuals, particularly for primary prevention.
Keyphrases
  • blood pressure
  • hypertensive patients
  • heart rate
  • risk assessment
  • blood glucose
  • type diabetes
  • combination therapy
  • skeletal muscle
  • climate change
  • big data
  • replacement therapy
  • smoking cessation
  • deep learning