Body composition and mortality in men receiving prostate radiotherapy: A pooled analysis of NRG/RTOG 9406 and NRG/RTOG 0126.

Andrew M McDonaldLyudmila DeMoraEddy S YangJohn M HoyleAndrew LenzieGrant R WilliamsJeff M MichalskiDon YeeJean-Paul BaharyRobert B DenMack RoachRobert T DessMark V MishraRichard K ValicentiHarold Y LauSamuel R MarcromLuis SouhamiLucas C MendezYuhchyau ChenDesiree E DoncalsStephanie L PughFelix Y FengHoward M Sandler

Published in: Cancer (2022)

This study strongly supports that body composition is related to mortality in men with localized PCa. The inclusion of psoas area in the RPA classification tree suggests that body composition provides additive information to age and comorbidity status for mortality prediction, particularly among older men. More research is needed to determine the clinical impact of body composition on prognostic models in men with PCa.

Keyphrases

body composition
resistance training
bone mineral density
middle aged
cardiovascular events
prostate cancer
risk factors
early stage
machine learning
radiation therapy
deep learning
squamous cell carcinoma
radiation induced
health information
social media
rectal cancer
benign prostatic hyperplasia
high intensity