PAI-1 and protein C as early markers of veno-occlusive disease in patients treated for Wilms tumor.

Simone Cesaro Margherita MauroGiulia SattinMaria Teresa SartoriGraziella SaggioratoAlessandra ParatellaGloria TridelloGianni Bisogno

Published in: Pediatric blood & cancer (2019)

PAI-1 Ag and protein C have good sensitivity and specificity for the diagnosis of VOD in WT patients. Their high negative predictive value can be used in the differential diagnosis of liver toxicity, especially in VOD episodes with absent or delayed hyperbilirubinemia.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
protein protein
peritoneal dialysis
extracorporeal membrane oxygenation
patient reported outcomes
highly efficient
patient reported