Postoperative acute pain management with duloxetine as compared to placebo: A systematic review with meta-analysis of randomized clinical trials.

Nishith Govil Pankaj Arora Kumar Parag Mukesh Tripathi Pankaj Kumar Garg Tarun Goyal

Published in: Pain practice : the official journal of World Institute of Pain (2023)

Based on GRADE findings, we conclude that there is low to moderate evidence to advocate the use of duloxetine for managing postoperative pain. Further trials are needed to replicate or refute these results based on robust methodology.

Keyphrases

pain management
postoperative pain
liver failure
chronic pain
patients undergoing
respiratory failure
double blind
drug induced
aortic dissection
high intensity
clinical trial
placebo controlled
study protocol