Quantitative measurement of IgG to SARS-CoV-2 proteins using ImmunoCAP.

Behnam KeshavarzJoesph R WiencekLisa J WorkmanMatthew D StraesserLyndsey M MuehlingGlenda CanderanFabrizio DragoCatherine A BonhamJeffrey M SturekChintan RamaniColeen A McNamaraJudith A WoodfolkAlexandra KadlThomas A E Platts-Mills Jeffrey M Wilson

Published in: medRxiv : the preprint server for health sciences (2020)

We have described a quantitative assay to measure IgG to SARS-CoV-2 that could be used in clinical and research laboratories and implemented at scale. The assay can easily be adapted to measure IgG to novel antigens, has good performance characteristics and a read-out in standardized units.

Keyphrases

sars cov
respiratory syndrome coronavirus
high throughput
high resolution
dendritic cells
immune response
single cell