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Polymer-mineral scaffold augments in vivo equine multipotent stromal cell osteogenesis.

Wei DuanCong ChenMasudul HaqueDaniel HayesMandi J Lopez
Published in: Stem cell research & therapy (2018)
In this study, both exogenous and host MSCs appear to contribute to in vivo osteogenesis. Addition of mineral to polymer scaffolds enhances equine MSC osteogenesis over polymer alone, but pure mineral scaffold provides superior osteogenic support. These results emphasize the need for bioscaffolds that provide customized osteogenic direction of both exo- and endogenous MSCs for the best regenerative potential.
Keyphrases
  • mesenchymal stem cells
  • tissue engineering
  • bone marrow
  • umbilical cord
  • cell therapy
  • bone regeneration
  • stem cells
  • single cell
  • risk assessment