Comparison of Genetic Profiles and Prognosis of High-Grade Gliomas Using Quantitative and Qualitative MRI Features: A Focus on G3 Gliomas.

Eun Kyoung Hong Seung Hong Choi Dong Jae Shin Sang Won Jo Roh-Eul Yoo Koung Mi Kang Tae Jin Yun Ji Hoon Kim Chul-Ho Sohn Hye-Kyung Park Jae Kyoung Won Tae Min Kim Chul-Kee Park Il Han Kim Soon Tae Lee

Published in: Korean journal of radiology (2020)

We found significant differences in MRI features, including volumetrics, CBV, and ADC, in G3 gliomas, according to IDH mutation and 1p/19q codeletion status, which can be utilized for the prediction of genomic profiles and the prognosis of G3 glioma patients. The MRI signatures and prognosis of IDHwt G3 gliomas tend to follow those of IDHwt GBMs.

Keyphrases

high grade
low grade
contrast enhanced
diffusion weighted imaging
magnetic resonance imaging
end stage renal disease
diffusion weighted
ejection fraction
chronic kidney disease
genome wide
computed tomography
copy number
magnetic resonance
systematic review
high resolution
gene expression
dna methylation