Mercaptopurine for the treatment of ulcerative colitis - a randomised placebo-controlled trial.

Mark LöwenbergAdriaan VolkersSara van GennepAart MookhoekNahid MontazeriEsmé ClasquinMarjolijn DuijvesteinAdriaan van BodegravenSvend RietdijkJeroen JansenDirk van AsseldonkEsmerij van der ZandenMarcel DijkgraafRachel WestNanne de BoerGeert D'Haens

Published in: Journal of Crohn's & colitis (2023)

Optimised mercaptopurine treatment was superior to placebo in achieving clinical, endoscopic and histological outcomes at one year following corticosteroid induction treatment in UC patients. More adverse events occurred in the mercaptopurine group.

Keyphrases

clinical trial
end stage renal disease
ulcerative colitis
chronic kidney disease
newly diagnosed
ejection fraction
study protocol
metabolic syndrome
skeletal muscle
replacement therapy
smoking cessation