The effect of Artemisia annua L. aqueous and methanolic extracts on insulin signaling in liver of HFD/STZ diabetic mice.

S Mohammad Reza Seyedi MoqadamMohammad Shokrzadeh LamukiForouzan SadeghimahalliMahshid Ghanbari

Published in: Journal of complementary & integrative medicine (2024)

extract ameliorated insulin resistance and improved insulin action in liver via the high activity of PI3K/AKt signaling pathway. So, it can be a suitable alternative treatment to synthetic antidiabetic drugs to improve insulin action in condition of type 2 diabetes.

Keyphrases

pi k akt
signaling pathway
type diabetes
glycemic control
insulin resistance
cell proliferation
high fat diet
cell cycle arrest
epithelial mesenchymal transition
oxidative stress
adipose tissue
induced apoptosis
metabolic syndrome
ionic liquid
cell death
endoplasmic reticulum stress
high fat diet induced