A kinetic resolution strategy for the synthesis of chiral octahedral NHC-iridium(iii) catalysts.
Romane ManguinDelphine PichonRobert TarrieuThomas VivesThierry RoisnelVincent DorcetChristophe CrévisyKarinne MiqueuLudovic FavereauJeanne CrassousMarc MauduitOlivier BasléPublished in: Chemical communications (Cambridge, England) (2019)
The transmetalation reaction of a chiral-bidentate NHC-silver complex to racemic [Ir(μ-Cl)(ppy)2]2 operates with kinetic resolution leading to chiral octahedral NHC-iridium(iii) complexes and enantio-enriched bis-cyclometalated iridium(iii) complexes. The iridium(iii) complexes demonstrated efficient catalytic activities in intermolecular [2+2] photocycloaddition reactions and in asymmetric Friedel-Crafts alkylations, respectively.