Distinct gene expression profiles associated with Notch ligands Delta-like 4 and Jagged1 in plaque material from peripheral artery disease patients: a pilot study.

Giorgio AquilaCinzia FortiniAntonio PannutiSerena DelbueMicaela PannellaMarco Bruno MorelliCristiana CalicetiFausto CastriotaMonica de MatteiAlessia OngaroAgnese PellatiPasquale FerranteLucio MieleLuigi TavazziRoberto FerrariPaola RizzoAlberto Cremonesi

Published in: Journal of translational medicine (2017)

This study reveals the existence of a gene signature associated to Notch activation by specific ligands that could be predictive of PAD progression.

Keyphrases

gene expression
peripheral artery disease
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
cell proliferation
dna methylation
coronary artery disease
prognostic factors
copy number
patient reported outcomes
transcription factor