Association of interleukin 2, interleukin 12, and interferon-γ with intervertebral disc degeneration in Iranian population.

Sara HanaeiSina AbdollahzadeMaryam SadrMohammad Hossein MirboloukEhsan FattahiAlireza KhoshnevisanNima Rezaei

Published in: BMC medical genetics (2020)

This study indicated the significant role of IL-2 genotypes and haplotypes in IVDD. These SNPs were differently distributed in patients and controls. Therefore, alteration in the structure of IL-2 gene could play an important role in pathophysiology of IVDD.

Keyphrases

end stage renal disease
genome wide
newly diagnosed
chronic kidney disease
ejection fraction
prognostic factors
peritoneal dialysis
dendritic cells
gene expression
dna methylation
immune response
neural network
patient reported