Adrenal suppression in patients with chronic obstructive pulmonary disease treated with glucocorticoids: Role of specific glucocorticoid receptor polymorphisms.

Pradeesh SivapalanStina Willemoes BorresenJosefin EklöfMarianne KloseFreja S HolmUlla Feldt-RasmussenMaria RossingNiklas R JørgensenRasmus Lykke MarvigMohamad Isam SaeedTorgny WilckeNiels SeersholmAlexander G MathioudakisJørgen VestboJens-Ulrik Stæhr Jensen

Published in: PloS one (2022)

In total, 5% of patients exhibited insufficient adrenal function. The Bcl1 and N363S polymorphisms did not seem to increase the risk of glucocorticoid suppression or metabolic disorders in adults treated with glucocorticoids for COPD exacerbations.

Keyphrases

chronic obstructive pulmonary disease
newly diagnosed
end stage renal disease
ejection fraction
chronic kidney disease
cystic fibrosis
peritoneal dialysis
prognostic factors
lung function
patient reported