Prognostic significance of immune checkpoints in the tumour-stromal microenvironment of sebaceous gland carcinoma.

Lata SinghMithalesh Kumar SinghMoshahid Alam RizviNeelam PushkerSameer BakhshiSeema Sen Rachna Meel

Published in: The British journal of ophthalmology (2020)

Our study highlights the prognostic outcome of PD-1 and PD-L1 protein expression in cells of tumour-stromal compartments. These results indicate that the PD-1/PD-L1 pathway mediates important interactions within the tumour microenvironment in SGC.

Keyphrases

bone marrow
stem cells
induced apoptosis
signaling pathway
endoplasmic reticulum stress