PTPRK, an EGFR Phosphatase, Is Decreased in CeD Biopsies and Intestinal Organoids.

Merlin NanayakkaraClaudia BellomoFrancesca FuroneMariantonia MaglioAntonella MaranoGiuliana LaniaMonia PorporaMartina NicolettiSalvatore AuricchioMaria Vittoria Barone

Published in: Cells (2022)

modulation of PTPRK levels can reduce or increase pEGFR, pERK and proliferation in CeD or CTR organoids, respectively. The CeD organoids can be a good model to study the mechanisms of the disease.

Keyphrases

small cell lung cancer
endoplasmic reticulum stress
tyrosine kinase
ultrasound guided
protein kinase