Kinetics of immune responses to the AZD1222/Covishield vaccine with varying dose intervals in Sri Lankan individuals.
Chandima JeewandaraInoka Sepali AberathnaLaksiri GomesPradeep Darshana PushpakumaraSaubhagya DanasekaraDinuka GurugeThushali RanasingheBanuri GunasekeraAchala KamaladasaHeshan KuruppuGayasha SomathilakeOsanda DissanayakeNayanathara GamalathDinithi EkanayakeJeewantha JayamaliDeshni JayathilakaAnushika MudunkotuwaMichael HarvieThashmi NimashaRuwan WijayamuniLisa SchimanskiPramila RijalTiong K TanTao DongAlain R TownsendGraham S OggGathsaurie Neelika MalavigePublished in: medRxiv : the preprint server for health sciences (2021)
Both dosing schedules resulted in high levels of antibody and T cell responses post vaccination, although those with a longer dosing gap had a higher magnitude of responses, possibly as immune responses were measured 6 weeks post second dose compared to 12 weeks post second dose.