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Prunella vulgaris polysaccharide inhibits herpes simplex virus infection by blocking TLR-mediated NF-κB activation.

Xuanlei ZhongYibo ZhangMan YuanLin XuXiaomei LuoRong WuZhichao XiYang LiHongxi Xu
Published in: Chinese medicine (2024)
Our results demonstrate that the P. vulgaris polysaccharide PVE30 is a potent anti-HSV agent that blocks TLR-mediated NF-κB activation.
Keyphrases
  • herpes simplex virus
  • nuclear factor
  • toll like receptor
  • inflammatory response
  • lps induced
  • signaling pathway
  • immune response
  • pi k akt
  • oxidative stress
  • cell proliferation
  • water soluble