Diabetes Risk Factors and Bone Microarchitecture as Assessed by High-Resolution Peripheral Quantitative Computed Tomography in Adults With Long-Standing Type 1 Diabetes.
Naina Sinha GregoryAndrew J BurghardtJye-Yu C BacklundMishaela R RubinIonut BebuBarbara H BraffettDavid J KennyThomas M LinkGalateia J KazakiaAnnette BarnieJohn M LachinRose A Gubitosi-KlugIan H de BoerAnn V Schwartznull nullPublished in: Diabetes care (2023)
Type 1 diabetes is associated with lower BMD, larger bone area, and poorer trabecular microarchitecture. Among participants with type 1 diabetes, suboptimal glycemic control, AGE accumulation, and microvascular complications are associated with deficits in bone microarchitecture and lower BMD.
Keyphrases
- glycemic control
- type diabetes
- bone mineral density
- risk factors
- high resolution
- blood glucose
- computed tomography
- postmenopausal women
- weight loss
- soft tissue
- insulin resistance
- bone regeneration
- bone loss
- cardiovascular disease
- traumatic brain injury
- body composition
- magnetic resonance imaging
- positron emission tomography
- adipose tissue
- metabolic syndrome
- magnetic resonance
- skeletal muscle
- chemotherapy induced