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Serum free light chain quantitative assays: Dilemma of a biomarker.

Giovanni CiglianaFrancesca GulliCecilia NapodanoKrizia PocinoElena De SantisLuigi ColaciccoIole CordoneLaura ContiUmberto Basile
Published in: Journal of clinical laboratory analysis (2017)
Our study highlights the importance of elaborating an international standard for free light chains quantification in order to offer homogeneous results as well as guarantee harmonization of values among laboratories. Moreover, the assays should be validated in specific patient groups to determine that they are clinically fit for purpose.
Keyphrases
  • high throughput
  • high resolution
  • mass spectrometry