Evaluation of an isothermal amplification HPV detection assay for primary cervical cancer screening.
Wei ZhangHui DuXia HuangChun WangXianzhi DuanYan LiuBin ShiWei ZhangXinfeng QuLihui WeiMark SchiffmanJ L BelinsonRuifang WuPublished in: Infectious agents and cancer (2020)
The AmpFire HPV assay showed similar sensitivity to Cobas and SeqHPV for CIN2+ and CIN3+ on both self and clinician-collections (P>0.05), with good specificity. The speed, low cost, and simplicity of this assay will make it particularly suited for low and middle resource settings. Its accuracy with self-collection makes it applicable for mass screening programs.