Microsurgical anatomy of language.
Clarissa Nunes VanacôrGustavo Rassier IsolanYang Han YuJoão Paulo Motta TellesDan Zimelewicz ObermanNícollas Nunes RabeloEberval Gadelha FigueiredoPublished in: Clinical anatomy (New York, N.Y.) (2020)
The localizationist model, which focused on classical cortical areas such as Broca's and Wernicke's, can no longer explain how language processing works. Over recent years, several studies have revealed new language-related cortical and subcortical areas, resulting in a transition from localizationist concepts to a hodotopical model. These studies have described language processing as an extensive and complex network of multiple interconnected cortical areas and subcortical pathways, differing from the classical circuit described by the localizationist perspective. The hodotopical model was made possible by a paradigm shift in the treatment of cerebral tumors, especially low-grade gliomas: total or subtotal tumor resections with cortical and subcortical mapping on awake patients have become the gold standard treatment for lesions located in the dominant hemisphere. In this article, we review current understating of the microsurgical anatomy of language.
Keyphrases
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- autism spectrum disorder
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- newly diagnosed
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- chronic kidney disease
- internal carotid artery
- subarachnoid hemorrhage
- combination therapy
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- single cell
- case control
- high density
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- replacement therapy
- breast reconstruction
- drug induced
- silver nanoparticles