Investigation of Neurological Complications after COVID-19 Vaccination: Report of the Clinical Scenarios and Review of the Literature.
Wei-Ping ChenMing-Hua ChenShih-Ta ShangYung-Hsi KaoKuo-An WuWen-Fang ChiangJenq-Shyong ChanHann-Yeh ShyuPo-Jen HsiaoPublished in: Vaccines (2023)
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), broke out in 2019 and became a pandemic in 2020. Since then, vaccines have been approved to prevent severe illness. However, vaccines are associated with the risk of neurological complications ranging from mild to severe. Severe complications such as vaccine-induced immune thrombotic thrombocytopenia (VITT) associated with acute ischaemic stroke have been reported as rare complications post-COVID-19 vaccination. During the pandemic era, VITT evaluation is needed in cases with a history of vaccination within the last month prior to the event. Cerebral venous sinus thrombosis (CVST) should be suspected in patients following immunization with persistent headaches who are unresponsive to analgesics. In this article, we investigated neurological complications after COVID-19 vaccination and provided more subsequent related clinical studies of accurate diagnosis, pathophysiological mechanisms, incidence, outcome, and management.
Keyphrases
- coronavirus disease
- sars cov
- respiratory syndrome coronavirus
- drug induced
- risk factors
- end stage renal disease
- early onset
- pulmonary embolism
- chronic kidney disease
- ejection fraction
- climate change
- cerebral ischemia
- peritoneal dialysis
- prognostic factors
- liver failure
- subarachnoid hemorrhage
- high glucose
- intensive care unit
- high resolution
- blood brain barrier