The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure.

Bernadet T SantemaMichelle M Y ChanJasper TrompMartin DokterHaye H van der WalJohanna E EmmensJanny TakensNilesh J SamaniLeong L NgChim C LangPeter van der MeerJozine M Ter MaatenKevin DammanKenneth DicksteinJohn G ClelandFaiez ZannadStefan D AnkerMarco MetraPim van der HarstRudolf A de BoerDirk J van VeldhuisenMichiel RienstraCarolyn S P LamCarolyn S P Lam

Published in: Clinical research in cardiology : official journal of the German Cardiac Society (2019)

These data show that in patients with HF, NT-proBNP is significantly influenced by underlying AF at time of measurement and not by previous episodes of AF, whereas the levels of GDF-15 are not influenced by the presence of AF. Therefore, GDF-15 might have additive value combined with NT-proBNP in the assessment of patients with HF and concomitant AF.

Keyphrases

atrial fibrillation
catheter ablation
oral anticoagulants
left atrial
left atrial appendage
direct oral anticoagulants
heart failure
percutaneous coronary intervention
electronic health record
acute heart failure
big data
venous thromboembolism
acute coronary syndrome
deep learning