Bilateral Focused Ultrasound Thalamotomy for Essential Tremor (BEST-FUS Phase 2 Trial).
Christian Iorio-MorinKazuaki YamamotoCan SaricaAjmal ZemmarMathieu LevesqueSimon BriseboisJurgen GermannAaron LohAlexandre BoutetGavin J B EliasPaula AzevedoElizabeth AdamUrmi PatelMartha LenisSuneil K KaliaMojgan HodaieAlfonso FasanoAndres M LozanoPublished in: Movement disorders : official journal of the Movement Disorder Society (2021)
Staged bilateral magnetic resonance-guided focused ultrasound thalamotomy can be performed with a reasonable safety profile similar to that seen with unilateral thalamotomy and improves the tremor and quality of life of patients with essential tremor. Longer-term follow-up and continued accrual in the phase 3 trial will be required to validate these findings. © 2021 International Parkinson and Movement Disorder Society.